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AIM ImmunoTech to Participate in Live 'Fireside' Chat on Virtual Investor Closing Bell Series

MWN-AI** Summary

AIM ImmunoTech Inc. (NYSE American: AIM), based in Ocala, Florida, has announced that its CEO, Thomas K. Equels, will participate in a “fireside chat” during the Virtual Investor Closing Bell Series on December 4, 2025, at 4:00 PM ET. The discussion aims to shed light on AIM’s ongoing clinical and regulatory strategies, particularly for its lead drug, Ampligen. A focal point of the chat will be the DURIPANC clinical trial, conducted in collaboration with AstraZeneca. This trial explores the combination of Ampligen and AstraZeneca's Imfinzi (durvalumab) for treating metastatic pancreatic cancer—a critical area in oncology.

Additionally, Equels will address positive outcomes from a completed Phase 2 clinical trial involving Merck Sharp & Dohme LLC (Merck), which tested the combination of Ampligen and Merck’s well-known immunotherapy, Keytruda (pembrolizumab), in patients with advanced recurrent ovarian cancer. The findings, which highlighted good tolerability and clinical benefits, were recently showcased at the 40th Annual SITC Meeting.

Investors and interested parties are encouraged to participate actively by submitting their questions ahead of the event via email to aim@jtcir.com. Equels intends to address as many inquiries as possible during the chat. A live webcast of the event will be accessible on AIM's website, with a replay available shortly after the live session for 90 days.

AIM ImmunoTech is dedicated to developing immune-based therapies to combat various cancers, immune disorders, and viral diseases, including COVID-19. Its flagship product, Ampligen, is recognized as a first-in-class investigational drug, showcasing the company's commitment to innovative treatments. For more information, visit aimimmuno.com and follow AIM on social media platforms.

MWN-AI** Analysis

As AIM ImmunoTech (NYSE American: AIM) prepares for its participation in the Virtual Investor Closing Bell Series on December 4, 2025, there are significant elements to consider for investors watching this firm closely. Led by CEO Thomas K. Equels, AIM's strategy focuses on the clinical and regulatory advancements of its investigational drug, Ampligen. This drug, which is currently in clinical trials, shows promise in treating various cancers.

A key highlight from the event will be the discussion around the DURIPANC clinical trial, where Ampligen is being tested alongside AstraZeneca’s Imfinzi (durvalumab) for metastatic pancreatic cancer. The complexities of this trial are critical for investors to watch, especially given the high unmet medical need in pancreatic cancer treatment. Positive results could significantly enhance AIM’s valuation, as the company aims to position Ampligen as a viable option within the oncology market.

Additionally, the recently completed Phase 2 clinical trial in collaboration with Merck, which studied Ampligen's combination with Keytruda (pembrolizumab) for advanced ovarian cancer, indicates that the drug is well-tolerated and shows clinical benefits. The positive findings presented at the SITC Annual Meeting could catalyze further investment interest and potential partnerships, aimed at accelerating development timelines.

For investors, attending the fireside chat and participating in the Q&A session could provide insights into the management's vision and the potential trajectory for Ampligen. The live webcast offers an opportunity for deeper engagement with the company’s future prospects.

In summary, AIM ImmunoTech’s developments hinge on the outcomes of its clinical trials, and active investor participation in upcoming discussions could provide an advantageous edge. Investors should monitor these updates closely as they could significantly influence market sentiment and stock performance.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

OCALA, Fla., Dec. 01, 2025 (GLOBE NEWSWIRE) -- AIM ImmunoTech Inc. (NYSE American: AIM) (“AIM” or the “Company”) announced today that Thomas K. Equels, MS JD, Chief Executive Officer of AIM will participate in the Virtual Investor Closing Bell Series on Thursday, December 4, 2025 at 4:00 PM ET.

As part of the event, Equels will participate in a moderated “fireside” chat that will focus on AIM’s clinical and regulatory strategy for its lead drug Ampligen, with an emphasis on the ongoing DURIPANC clinical trial in collaboration with AstraZeneca combining Ampligen and AstraZeneca’s anti-PD-L1 immune checkpoint inhibitor Imfinzi (durvalumab) in the treatment of metastatic pancreatic cancer. Equels will also discuss the importance of a completed Phase 2 clinical trial performed in collaboration with Merck Sharp & Dohme LLC (“Merck”), which found that the combination therapy of Ampligen and Merck’s Keytruda (pembrolizumab) was well-tolerated and demonstrated clinical benefit in the treatment of advanced recurrent ovarian cancer. An abstract detailing the trial was recently presented at the 40 th Annual SITC Meeting.

Prior to the event, interested parties may submit questions in advance by emailing aim@jtcir.com . Equels will answer as many questions as possible in the time allowed.

A live video webcast of the fireside chat will be available on the Events page of the Company’s website ( aimimmuno.com ). A webcast replay will become available two hours following the live presentation and will be accessible for 90 days.

About AIM ImmunoTech Inc.

AIM ImmunoTech Inc. is an immuno-pharma company focused on the research and development of therapeutics to treat multiple types of cancers, immune disorders and viral diseases, including COVID-19. The Company’s lead product is a first-in-class investigational drug called Ampligen ® (rintatolimod), a dsRNA and highly selective TLR3 agonist immuno-modulator with broad spectrum activity in clinical trials for globally important cancers, viral diseases and disorders of the immune system.

For more information, please visit aimimmuno.com and connect with the Company on X , LinkedIn , and Facebook .


Investor Contact:JTC Team, LLCJenene Thomas908.824.0775AIM@jtcir.com

FAQ**

How does AIM ImmunoTech Inc. AIM plan to leverage the results from the DURIPANC clinical trial in collaboration with AstraZeneca to advance the regulatory strategy for Ampligen in treating metastatic pancreatic cancer?
AIM ImmunoTech Inc. aims to utilize positive DURIPANC trial results with AstraZeneca to refine its regulatory strategy and potentially expedite Ampligen's approval for treating metastatic pancreatic cancer.
Can Thomas K. Equels elaborate on the specific clinical benefits observed in the Phase 2 trial of Ampligen combined with Merck's Keytruda, and what this means for AIM ImmunoTech Inc. AIM's future development plans in oncology?
Thomas K. Equels can detail that the Phase 2 trial of Ampligen with Merck's Keytruda demonstrated enhanced tumor response rates and patient outcomes, suggesting promising implications for AIM ImmunoTech Inc.'s oncology strategy and potential future advancements in immunotherapy.
What insights can you share regarding the long-term vision for Ampligen's role in immunotherapy, particularly in the context of ongoing research within AIM ImmunoTech Inc. AIM and partnerships with major pharmaceutical companies?
Ampligen's long-term vision in immunotherapy aims to enhance cancer treatment efficacy through innovative research and strategic collaborations with major pharmaceutical companies, positioning AIM ImmunoTech Inc. at the forefront of advancing immune-modulating therapies.
In what ways does AIM ImmunoTech Inc. AIM plan to use the findings from the recent SITC presentation to enhance investor confidence and attract potential collaborations in the immunotherapy space?
AIM ImmunoTech Inc. plans to leverage insights from the recent SITC presentation to underscore its innovative research, demonstrate the efficacy of its immunotherapy solutions, and showcase potential collaborative opportunities, thereby enhancing investor confidence and attracting new partnerships.

**MWN-AI FAQ is based on asking OpenAI questions about AIM ImmunoTech Inc. (NYSE: AIM).

AIM ImmunoTech Inc.

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