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Santhera Appoints Stifel as Corporate Finance Advisor

MWN-AI** Summary

On February 10, 2026, Santhera Pharmaceuticals, a Swiss company listed on the SIX Swiss Exchange under the ticker SANN, announced its strategic appointment of Stifel Nicolaus Europe Limited as a corporate finance advisor. This partnership aims to enhance the company’s capital markets initiatives and broaden its outreach to international institutional investors. Stifel will work in conjunction with Octavian AG, which has been maintaining an advisory role, to expand the company's investor engagement and market presence, particularly in the context of financing and strategic growth.

Santhera Pharmaceuticals specializes in developing and commercializing innovative treatments for rare neuromuscular diseases, addressing significant unmet medical needs. Notably, the company holds an exclusive global license for AGAMREE® (vamorolone), a unique dissociative steroid designed as an alternative treatment for Duchenne muscular dystrophy (DMD), a severe genetic disorder affecting muscle degeneration. AGAMREE has received regulatory approval from multiple health authorities, including the FDA in the U.S. and the European Commission, signifying its viability and the potential impact on patients with DMD.

In addition to its direct offerings, Santhera has established partnerships for AGAMREE’s distribution in various regions: Catalyst Pharmaceuticals manages its North America rights, while Sperogenix Therapeutics and Nxera Pharma handle distribution in China and specified Asia-Pacific markets, respectively.

The collaboration with Stifel is expected to reinforce Santhera’s growth trajectory, as the company seeks to attract wider investor interest while continuing its commitment to developing essential therapeutic solutions for underserved patient populations.

MWN-AI** Analysis

Santhera Pharmaceuticals’ recent appointment of Stifel Nicolaus as a corporate finance advisor, alongside ongoing collaboration with Octavian AG, signals a strategic move aimed at enhancing capital market presence and engaging international institutional investors. This development comes at a pivotal time for Santhera, especially with its flagship product, AGAMREE® (vamorolone), gaining traction in multiple regulated markets.

Investors should view this dual advisory relationship positively, as it may facilitate improved access to funding, strategic partnerships, and enhanced visibility within the global capital markets. Stifel’s established network can be instrumental in connecting Santhera with larger institutional investors, potentially driving stock liquidity and investor confidence.

Santhera's focus on innovative treatments for rare neuromuscular diseases positions it uniquely within the biopharmaceutical sector, particularly as AGAMREE® addresses high unmet medical needs in patient populations, such as those suffering from Duchenne muscular dystrophy (DMD). The recent regulatory approvals from major markets, including the U.S., EU, and Canada, underline the product's viability and its commercial potential.

However, while optimism is warranted, investors should maintain a cautious outlook due to inherent market risks, including potential delays in further approvals and the competitive landscape within the rare disease sector. Furthermore, international collaborations, as seen with the out-licensing of AGAMREE® to various partners, will be crucial in expanding market reach and revenues.

In summary, Santhera's strategic initiatives to enhance its capital market footprint through Stifel and Octavian, combined with its promising pipeline, presents an attractive opportunity for investors. Nevertheless, careful evaluation of market conditions and company performance will be essential in navigating potential risks inherent in the biopharmaceutical industry.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

Pratteln, Switzerland, February 10, 2026 – Santhera Pharmaceuticals (SIX: SANN) today announced the appointment of Stifel Nicolaus Europe Limited (“Stifel”) as corporate finance advisor with a focus on capital markets and international institutional investors.

Swiss based Octavian AG (“Octavian”) will continue to act as corporate finance advisor to the Company, working alongside Stifel to help broaden investor reach.

About Santhera
Santhera Pharmaceuticals (SIX: SANN) is a Swiss specialty pharmaceutical company focused on the development and commercialization of innovative medicines for rare neuromuscular diseases with high unmet medical need. The Company has an exclusive license from ReveraGen for all indications worldwide to AGAMREE® (vamorolone), a dissociative steroid with novel mode of action, which was investigated in a pivotal study in patients with Duchenne muscular dystrophy (DMD) as an alternative to standard corticosteroids. AGAMREE for the treatment of DMD is approved in the U.S. by the Food and Drug Administration (FDA), in the EU by the European Commission (EC), in the UK by the Medicines and Healthcare products Regulatory Agency (MHRA), in Switzerland by Swissmedic, in China by the National Medical Products Administration (NMPA), in Hong Kong by the Department of Health (DoH) and in Canada by Health Canada. Santhera has out-licensed the rights to AGAMREE as follows: to Catalyst Pharmaceuticals for North America; to Sperogenix Therapeutics for China and certain countries in Southeast Asia; and to Nxera Pharma for Japan, South Korea, Australia, and New Zealand. For further information, please visit www.santhera.com.

AGAMREE® is a trademark of Santhera Pharmaceuticals.

For further information please contact:

Santhera
Catherine Isted, Chief Financial Officer:

IR@santhera.com

ICR Healthcare:

Santhera@icrhealthcare.com

Stifel                                            +44 (0)20 7710 7600
Brough Ransom, Charles Hoare, Fred Walsh

Octavian                                        +41 (0)44 520 15 88
Serge Monnerat, Marius Zuberbuehler

Disclaimer / Forward-looking statements
This communication does not constitute an offer or invitation to subscribe for or purchase any securities of Santhera Pharmaceuticals Holding AG. This publication may contain certain forward-looking statements concerning the Company and its business. Such statements involve certain risks, uncertainties and other factors which could cause the actual results, financial condition, performance or achievements of the Company to be materially different from those expressed or implied by such statements. Readers should therefore not place undue reliance on these statements, particularly not in connection with any contract or investment decision. The Company disclaims any obligation to update these forward-looking statements.

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FAQ**

How will the appointment of Stifel Nicolaus Europe Limited as a corporate finance advisor influence the strategic direction of Santhera Pharms Hldgs Ltd SPHDF in attracting international institutional investors?

The appointment of Stifel Nicolaus Europe Limited as a corporate finance advisor is likely to enhance Santhera Pharmaceuticals' strategic direction by leveraging their expertise to improve investor relations, increase market visibility, and effectively attract international institutional investors.

Given that Santhera Pharms Hldgs Ltd SPHDF has secured various international approvals for AGAMREE®, what are the plans for expanding market penetration in regions where it has been out-licensed?

Santhera Pharmaceuticals plans to leverage its international approvals for AGAMREE® by enhancing partnerships with local distributors, increasing marketing efforts, and focusing on regulatory compliance to expand market penetration in out-licensed regions effectively.

In what ways do Santhera Pharms Hldgs Ltd SPHDF and Octavian AG plan to collaborate to enhance overall investor outreach and communication strategies moving forward?

Santhera Pharmaceuticals and Octavian AG plan to collaborate by leveraging combined expertise in targeted outreach initiatives and enhanced digital communication strategies to better engage investors and improve transparency regarding corporate developments and strategic objectives.

How does Santhera Pharms Hldgs Ltd SPHDF assess the risks and uncertainties surrounding its forward-looking statements regarding future performance and market conditions in the pharmaceutical sector?

Santhera Pharmaceuticals evaluates risks and uncertainties related to future performance and market conditions by analyzing industry trends, regulatory changes, competitive dynamics, and financial forecasts, while incorporating both quantifiable metrics and qualitative insights.

**MWN-AI FAQ is based on asking OpenAI questions about Santhera Pharms Hldgs Ltd (OTC: SPHDF).

Santhera Pharms Hldgs Ltd

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