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Silexion Therapeutics to Attend 7th Annual RNAi-Based Therapeutics Summit

MWN-AI** Summary

Silexion Therapeutics Corp., an innovative, clinical-stage biotechnology company focused on oncology, has announced its participation in the 7th Annual RNAi-Based Therapeutics Summit scheduled for January 27-29, 2026, in Boston, MA. The company’s management team, including CEO Ilan Hadar, will engage in one-on-one meetings during the summit to discuss their advancements and future plans in RNA-based therapeutics. As a premier forum in the industry, this event gathers drug developers to explore RNA-based treatments for various diseases, including oncology.

A key highlight for Silexion is its development of SIL204, a cutting-edge small interfering RNA (siRNA) therapy aimed at targeting mutated KRAS oncogenes, recognized as a leading factor in human cancers. The company is preparing to initiate a Phase 2/3 clinical trial in mid-2026 focused on locally advanced pancreatic cancer, a condition currently fraught with limited treatment options. Silexion’s previous clinical efforts include a successful Phase 2a trial of its first-generation product, which demonstrated promising outcomes compared to standard chemotherapy.

As an official partner of the RNAi-Based Therapeutics Summit for 2026, Silexion aims to highlight its dedication to advancing therapeutic solutions for patients with solid tumor cancers linked to KRAS mutations. The company is committed to pushing the envelope in cancer treatment and continues to work on refining its lead product candidate. For more information, interested individuals may visit Silexion's website or reach out to their Investor Relations team. With its focus on innovation and patient care, Silexion is poised to make impactful contributions to the oncology space.

MWN-AI** Analysis

Silexion Therapeutics Corp. is positioning itself as a key player in the oncology landscape with its innovative siRNA therapy, SIL204, aimed at silencing mutated KRAS oncogenes, a prominent driver in various cancers. The company’s active participation in the 7th RNAi-Based Therapeutics Summit in January 2026 presents both an opportunity and a strategic move to enhance its visibility among drug developers and investors.

With SIL204 set to enter a Phase 2/3 clinical study for locally advanced pancreatic cancer, investor sentiment could see a favorable uptick. The historical context is promising—Silexion's Phase 2a trial results hint at efficacy beyond traditional chemotherapy, potentially marking a paradigm shift in treating aggressive solid tumors characterized by KRAS mutations.

The biotech sector is characterized by its volatility, but Silexion’s targeted approach aligns well with current trends favoring precision medicine. As the company partners with leading forums such as the RNAi Summit, it’s likely to garner interest from both institutional investors and industry stakeholders, ultimately driving shareholder value.

Given the promising preclinical results and the strategic partnerships illustrated by its involvement at the summit, Silexion might be a valuable consideration for investors seeking exposure to cutting-edge biotherapeutics in oncology. However, as always, potential investors should remain cautious. The path through clinical trials can be unpredictable, and competition in the oncology space is fierce.

In summary, Silexion Therapeutics holds potential but warrants close monitoring of its clinical developments and market positioning. For investors looking to diversify into biotech, Silexion could offer both growth potential and volatility given the high stakes typically involved in drug development. Engaging with their Investor Relations prior to the summit might provide additional insights into strategic objectives and anticipated outcomes.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

Grand Cayman, Cayman Island, Jan. 21, 2026 (GLOBE NEWSWIRE) -- Silexion Therapeutics Corp. (“Silexion” or the “Company”), a clinical-stage, oncology-focused biotechnology company, today announced that Company management, including CEO Ilan Hadar, will attend the 7th RNAi-Based Therapeutics Summit, taking place January 27-29 in Boston, MA. ?

The?7th RNAi-Based Therapeutics Summit?is the industry's premier forum inviting drug developers to discuss RNA-based therapeutics for neurological, metabolic, cardiovascular, and oncological diseases. Silexion is developing SIL204, a next-generation siRNA therapy designed to silence mutated KRAS oncogenes - the most common oncogenic driver in human cancers. SIL204 is planned to enter a Phase 2/3 clinical study program in locally advanced pancreatic cancer in mid 2026.

Silexion management will host one-on-one meetings during the summit. Interested parties should contact the Company’s Investor Relations representatives who can arrange such meetings.

Silexion is pleased to be an official partner of the RNAi-Based Therapeutics Summit?for 2026.

About Silexion Therapuetics
Silexion Therapeutics is a pioneering clinical stage, oncology-focused biotechnology company dedicated to the development of innovative treatments for unsatisfactorily treated solid tumor cancers which have the mutated KRAS oncogene, generally considered to be the most common oncogenic gene driver in human cancers. The Company conducted a Phase 2a clinical trial in its first-generation product which showed a positive trend in comparison to the control of chemotherapy alone. Silexion is committed to pushing the boundaries of therapeutic advancements in the field of oncology, and further developing its lead product candidate for locally advanced pancreatic cancer. For more information please visit: https://silexion.com

Company Contact:
Silexion Therapeutics Corp
Ms. Mirit Horenshtein Hadar, CFO
mirit@silexion.com

Investor Relations
Arx Investor Relations
North American Equities Desk
silexion@arxhq.com


FAQ**

What key milestones can investors expect from Silexion Therapeutics Corp (SLXN) leading up to the anticipated Phase 2/3 clinical study for SIL204 in mid-2026?

Investors can expect key milestones from Silexion Therapeutics Corp (SLXN) including pre-clinical results, regulatory submissions, patient recruitment updates, and interim data analyses as they progress toward the anticipated Phase 2/3 clinical study for SIL204 in mid-2026.

How does Silexion Therapeutics Corp (SLXN) plan to differentiate SIL204 from other oncology therapies targeting the mutated KRAS oncogene?

Silexion Therapeutics Corp (SLXN) aims to differentiate SIL204 by employing a novel dual-action mechanism that selectively targets the mutated KRAS oncogene while minimizing off-target effects, thereby enhancing efficacy and reducing toxicities compared to existing therapies.

What insights into the RNAi-focused development strategy can Silexion Therapeutics Corp (SLXN) share during the 7th RNAi-Based Therapeutics Summit?

Silexion Therapeutics Corp (SLXN) can share insights on their innovative approaches to enhancing RNAi efficacy, minimizing off-target effects, and advancing their pipeline of therapeutics aimed at treating a range of diseases during the 7th RNAi-Based Therapeutics Summit.

Can Silexion Therapeutics Corp (SLXN) provide updates on the Phase 2a clinical trial results and their implications for future product development?

As of my last update in October 2023, Silexion Therapeutics Corp (SLXN) has not publicly shared the results of the Phase 2a clinical trial; please check their official communications for any recent updates or implications for future product development.

**MWN-AI FAQ is based on asking OpenAI questions about Silexion Therapeutics Corp (NASDAQ: SLXN).

Silexion Therapeutics Corp

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