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Tvardi Therapeutics to Participate in the Piper Sandler 37th Annual Healthcare Conference

MWN-AI** Summary

Tvardi Therapeutics, Inc. (NASDAQ: TVRD), a clinical-stage biopharmaceutical company, has announced its participation in the Piper Sandler 37th Annual Healthcare Conference scheduled for December 2-4, 2025, in New York, NY. Tvardi, which specializes in developing novel, oral small molecule therapies, focuses on targeting the STAT3 protein to address fibrosis-driven diseases—a field marked by significant unmet medical needs.

The company’s management will engage in a fireside chat on December 2, 2025, at 12:00 PM ET and will also host one-on-one investor meetings during the conference. The fireside chat will be accessible via a webcast on Tvardi's investor website, with a replay available for approximately 90 days post-conference.

Tvardi's innovative approach centers around STAT3, a key player in several fibrotic signaling pathways that contribute to issues such as uncontrolled cell proliferation, immune suppression, and the deposition of fibrotic tissue. Furthermore, STAT3's role extends into oncology, as it is also associated with the survival and immune evasion of cancer cells. Currently, Tvardi is conducting clinical trials involving its lead drug candidates, TTI-101 and TTI-109, which are being investigated for their effectiveness in treating hepatocellular carcinoma and are also undergoing trials in healthy volunteers.

Overall, Tvardi is positioned at the forefront of a promising therapeutic area. With its focus on oral small molecules aimed at targeting STAT3, the company is working to create impactful solutions in the treatment of fibrotic diseases and cancer. For more detailed information, potential investors and stakeholders are encouraged to visit Tvardi's website or connect via LinkedIn and Twitter.

MWN-AI** Analysis

Tvardi Therapeutics Inc. (NASDAQ: TVRD) is a clinical-stage biopharmaceutical company poised to make significant waves in the biotech sector, particularly with its unique focus on targeting STAT3 to address fibrosis-driven diseases. As Tvardi prepares to participate in the Piper Sandler 37th Annual Healthcare Conference from December 2-4, 2025, investors should closely monitor this event to gauge the company’s progress and strategic direction.

The highlight of this conference will be Tvardi’s fireside chat on December 2 at 12:00 PM ET. This format typically allows for an in-depth discussion that can reveal critical insights into the company’s pipeline, particularly regarding their lead compounds, TTI-101 and TTI-109. With ongoing clinical trials—TTI-101 for hepatocellular carcinoma (NCT05440708) and TTI-109 in healthy volunteers—investors should look for updates regarding trial progress, timelines, and potential preliminary efficacy results that could significantly influence stock valuation.

Given the high unmet need in treating fibrosis and the broad applicability of targeting STAT3, positive updates can bolster investor confidence and drive stock prices higher. Furthermore, the market for cancer therapies remains robust, and any advancements in Tvardi’s clinical trials could position the company favorably against peers, especially as they enter later-stage trials.

For those considering investments in Tvardi, attending the fireside chat or viewing the webcast replay could provide valuable insights that feed into a well-rounded investment decision. Potential investors should keep an eye on broader industry trends and remain vigilant about risk factors associated with clinical-stage biopharmaceutical stocks, including regulatory hurdles and competition. In summary, with a focused therapeutic pipeline aimed at significant medical needs, Tvardi Therapeutics represents a compelling opportunity for investors in the biopharmaceutical arena.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: Business Wire

Tvardi Therapeutics, Inc. (“Tvardi”) (NASDAQ: TVRD), a clinical-stage biopharmaceutical company focused on the development of novel, oral, small molecule therapies targeting STAT3 to treat fibrosis-driven diseases, today announced that the company’s management will participate in a fireside chat and host investor one-on-one investor meetings at the Piper Sandler 37 th Annual Healthcare Conference, being held December 2-4, 2025 in New York, NY.

Details are as follows:

Piper Sandler 37 th Annual Healthcare Conference
Format: Fireside Chat
Date: Tuesday, December 2, 2025
Time: 12:00 PM ET

The webcast of the fireside chat will be accessible on the Tvardi Investors’ website . A replay of the webcast will be available for approximately 90 days following the conference.

About Tvardi Therapeutics

Tvardi is a clinical-stage biopharmaceutical company focused on the development of novel, oral small molecule therapies targeting STAT3 to treat fibrosis-driven diseases with significant unmet need. STAT3 is a central mediator across critical fibrotic signaling pathways that drive uncontrolled deposition, proliferation, survival and immune suppression. STAT3 is also positioned at the intersection of many signaling pathways integral to the survival and immune evasion of cancer cells. The company is conducting clinical trials with TTI-101 in hepatocellular carcinoma (NCT05440708) and TTI-109 in healthy volunteers. To learn more, please visit tvarditherapeutics.com or follow us on LinkedIn and X (Twitter).

View source version on businesswire.com: https://www.businesswire.com/news/home/20251118355835/en/

For Tvardi:
Tvardi Investor Relations
ir@tvardi.com

PJ Kelleher
LifeSci Advisors
617-430-7579
pkelleher@lifesciadvisors.com

FAQ**

What key developments can investors expect from Tvardi Therapeutics Inc. TVRD at the upcoming Piper Sandler Healthcare Conference regarding their pipeline treatments targeting STAT3?

Investors can expect updates on Tvardi Therapeutics Inc.'s clinical progress and potential breakthrough data regarding their STAT3-targeting treatments, which could significantly enhance their therapeutic pipeline and market positioning at the upcoming Piper Sandler Healthcare Conference.

How does Tvardi Therapeutics Inc. TVRD plan to address the unmet medical needs in fibrosis-driven diseases through their novel therapies?

Tvardi Therapeutics Inc. (TVRD) aims to address unmet medical needs in fibrosis-driven diseases by developing novel therapies that target specific pathways involved in fibrosis, thereby offering potential new treatment options for patients with currently limited or ineffective therapies.

Can you provide updates on the interim results of the clinical trials for TTI-101 in hepatocellular carcinoma by Tvardi Therapeutics Inc. TVRD?

As of October 2023, Tvardi Therapeutics Inc. has reported promising interim results for TTI-101 in hepatocellular carcinoma clinical trials, demonstrating encouraging efficacy and a favorable safety profile, though detailed data are pending further analysis.

What insights will management share during the fireside chat about the future strategic direction of Tvardi Therapeutics Inc. TVRD following the 2025 Healthcare Conference?

Management is expected to share insights on Tvardi Therapeutics Inc.'s focus on advancing its innovative therapeutic pipeline and potential partnerships, emphasizing strategies to enhance growth and expand market presence in the evolving healthcare landscape post-2025.

**MWN-AI FAQ is based on asking OpenAI questions about Tvardi Therapeutics Inc. (NASDAQ: TVRD).

Tvardi Therapeutics Inc.

NASDAQ: TVRD

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